The trigeminal ganglion is implicated in the underlying pathology of migraine and temporomandibular joint disorders (TMD). which are orofacial pain conditions involving peripheral and central sensitization. The neuropeptide calcitonin gene-related peptide (CGRP) is synthesized in some trigeminal ganglion neurons. and its release promotes inflammation. https://www.marcelovicente.com/product-category/color-freeze-conditioner/